Isobutyl alcohol 2905149000
- Synonyms: Isobutyl alcohol, 2-methylpropanol-1, isopropylcarbinnol
- T bp: 107.89 ° C
- Freezing point: -108.00 ° С
Itakura obtained Isobutyl alcohol by catalytic hydration of butylene in the presence of sulfuric acid. The maximum yield (25%) was achieved when using 50% sulfuric acid and carrying out the reaction at 105 °.
For purification, Brunel boiled commercial Isobutyl alcohol with lime for 5 hours, and then in continued 1.5 hours with calcium shavings. The dried alcohol was then thoroughly fractionated several times on an efficient column.
Michael, Scharf and Voight fractionated pure commercial alcohol on a high Hempel column to a constant boiling point (within 0.15 °). The yield was 400 g per 1000 g of the starting preparation. After shaking with dilute sulfuric acid to remove base impurities, the alcohol was washed with water and dried first over calcined potash and then over lime. Next, the alcohol was purified by converting it into a boric acid ester by heating for 6 hours at 160-175 ° in an autoclave with boric acid, the amount of which was a quarter (by weight) of the amount of alcohol. The ether was fractionated several times in vacuum and then hydrolyzed by short-term heating with aqueous alkali. After drying over lime, the alcohol was distilled.
Hückel and Ackermann converted Isobutyl alcohol into acidic phthalate by heating it with phthalic anhydride; ether was recrystallized from petroleum ether to constant melting point (65 °), after which it was hydrolyzed with 15% potassium hydroxide solution. Then the alcohol was distilled in the form of an azeotropic mixture with water, dried over potash, anhydrous copper sulfate, and finally over magnesium shavings. Finally, the alcohol was subjected to fractional distillation.
Matthews dried technical isobutyl alcohol several times with barium oxide, after which he thoroughly distilled it. The dried substance was used to determine the heat of vaporization.
For conductivity measurements, Goldschmidt dried and purified the alcohol by re-treating with calcium or treating with aluminum amalgam. The dehydrated preparation was then subjected to fractional distillation over sulfanilic or tartaric acid.
The rate of esterification with phenylacetic acid can serve as a criterion for the degree of dehydration.
Toxicology. The toxic effect of isobutyl alcohol on animals is similar to that of n-butyl alcohol. It is slightly less toxic by inhalation than n-butyl or sec-butyl alcohols. Fassett (unpublished data) showed that humans tolerate a concentration of 0.01% well.
The lower flammability limit in air is 1.68 vol. %.
The data are taken from the reference book A. Weisberger, E. Proskauer, J. Riddick, E. Toops Organic solvents. - M.: Izdatinlit, 1958.
- Dipole moment: 1.79
- Dielectric constant: 17.7 at 25 ° C
- dTboil / dP: 0.036
- Density: 0.80576 at 15 ° C
- Refractive index: 1.3939 at 25 ° C
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Here you can carry out a complex purchase of goods, both for production and for subsequent sale. You can not only purchase products from us, but also get advice on the technological application of the purchased raw materials, receive guidelines and other information./ span>
Here you can carry out a complex purchase of goods, both for production and for subsequent sale. You can not only purchase products from us, but also get advice on the technological application of the purchased raw materials, receive guidelines and other information.